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Supercharged Penicillin

Scientists Produce New Bacteria-Resistant Penicillin with Modified Fungus

— January 25, 2013 — Lifestyle
Despite being one of the most important medical discoveries of the 20th century, many strains of bacteria have become resistant to penicillin. The drug, produced from a fungus known as Penicillium chrysogenum, is slowly going obsolete because of evolution in disease-causing bacteria. This is a big problem, because the fungus produces asexually, which means that there's not enough genetic diversity in the chemical makeup of the fungus. This means that there are only so many configurations of penicillin, and as far as bacteria are concerned, the jig is up.

However, hope is on the horizon in the battle against diseases resistant to penicillin. Scientists have induced sexual, rather than asexual reproduction in a strain of the fungus, greatly enhancing its genetic diversity and keeping bacteria on their toes. That is, if bacteria had toes...

The researchers are also touting economic as well as the medical benefits of their find.
Trend Themes
1. Enhanced Genetic Diversity - The induced sexual reproduction of the Penicillium chrysogenum fungus provides an opportunity for enhanced genetic diversity in penicillin, combating bacteria resistance.
2. Bacteria-resistant Medicines - The development of bacteria-resistant penicillin opens the door for the creation of other medicines that are capable of combating evolving bacteria strains.
3. Advancements in Medical Research - The discovery of new ways to combat bacteria resistance to penicillin demonstrates the potential for advancements in medical research and the treatment of various diseases.
Industry Implications
1. Pharmaceuticals - Pharmaceutical companies can explore the development of bacteria-resistant drugs by incorporating genetic diversity techniques used in the modified penicillin.
2. Biotechnology - Biotechnology companies can leverage genetic manipulation methods to enhance the effectiveness of existing drugs and develop new treatments for antibiotic-resistant bacteria.
3. Research and Development - Research institutions can focus on studying and enhancing the genetic diversity of organisms to develop innovative solutions that combat bacteria resistance.
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