Elysium Health has published new research in Frontiers in Aging demonstrating that its flagship NAD+-boosting supplement — Basis — significantly reduced the frequency and severity of disruptive menopausal symptoms, including hot flashes, bloating, and poor sleep, in women over age 35 who self-reported symptoms associated with the menopause transition. The research also showed a beneficial increase in the ratio of estradiol to estrone, two key forms of estrogen, and characterized a previously unreported NAD+ metabolite that expands scientific understanding of how NAD+ precursors are metabolized in humans.
The open-label pilot study in Frontiers in Aging enrolled 40 healthy women, 32 of whom experienced menopausal symptoms and eight who did not. After seven days of Basis supplementation, the symptomatic group reported reductions of 50% or more in several of the most bothersome symptoms.
Image Credit: Elysium Health
What's Driving This Trend
- Menopause-focused Longevity Supplements
- Clinically studied NAD+-boosting formulas are creating space for targeted midlife wellness products that address hormonal symptoms beyond conventional menopause care.
- Biomarker-driven Nutraceuticals
- New metabolite and hormone-ratio findings point to supplement platforms that pair consumer wellness claims with measurable biological endpoints.
- Women-centered Healthy Aging
- Research linking cellular health ingredients to sleep, hot flashes, and bloating signals a growing market for age-specific wellness solutions designed around women’s lived symptoms.
Who This Affects Most
- Nutraceuticals
- Evidence-backed supplement brands are positioned to differentiate through peer-reviewed research, novel metabolite discovery, and condition-specific formulations.
- Femtech
- Menopause symptom tracking and personalized wellness platforms can integrate validated supplements into broader digital care experiences for women over 35.
- Longevity Medicine
- NAD+ research expands the commercial relevance of cellular aging interventions into everyday symptom management and preventive health programs.
