German artist Markus Reugels uses a high-speed camera to capture tiny droplets of water as they show a refraction of the background, which is usually a large satellite image. The shots would undoubtedly require impeccable timing, but seem well worth it. The droplets create an incredible photo series that are so interesting, they seem to be helped with some kind of magical intervention. Although, the photo of Reugels' work station certainly helps us imagine what the extent of the process must be like. Markus Reugals actually takes requests that would allow you to choose whichever backdrop you would like, while he also sells prints in several sizes.
While by definition photo manipulation usually takes place during post-production editing, this interesting technique arguably offers similar results.