# Flexible Tablet Coaters Syntegon's Sepion 75 Scales Pharmaceutical Batch Processing By Mursal Rahman | Written with AI assistance | Published 2026-09-01 | Tech Source: Trend Hunter, https://www.trendhunter.com/trends/Flexible-tablet-coaters References: [packagingeurope](https://packagingeurope.com/news/syntegon-reveals-pilot-scale-tablet-coater-for-variable-batch-sizes/14630.article) & [syntegon](https://www.syntegon.com/press/syntegon-expands-sepion-series-with-new-pilot-scale-tablet-coater/)  [Flexible tablet coaters](https://www.trendhunter.com/trends/mettlertoledo-x6-series) are supporting more adaptable pharmaceutical manufacturing as Syntegon expands its Sepion series with the pilot-scale Sepion 75. Designed for batch volumes from eight to 75 liters, the system can process between 10% and 100% of its maximum working volume using two interchangeable drums. Consistent process principles allow manufacturers to transfer parameters from pilot development to commercial production without redefining coating conditions. Closed material handling and optional OEB5 containment also support safer processing of [highly potent active ingredients](https://www.trendhunter.com/trends/log-pharma). For pharmaceutical manufacturers and CDMOs, this flexibility can make it easier to manage growing product portfolios and increasingly variable batch requirements. [Faster changeovers and reproducible coating conditions](https://www.trendhunter.com/trends/parker-food-group) could reduce downtime while simplifying scale-up between development and production. For Syntegon, extending the Sepion portfolio to pilot-scale applications creates a more complete equipment ecosystem, strengthening its ability to support customers throughout pharmaceutical development and commercial manufacturing. Image Credit: Syntegon ## Trend Insights (Trend Hunter) - Score: 8.1/10 - Popularity: 62% | Activity: 90% | Freshness: 92% - Audience gender: 50% men, 50% women - Primary generations: Millennial, Gen X - Top markets: North America, Europe ## Categories [Trend Hunter](https://www.trendhunter.com/trends) > [Tech](https://www.trendhunter.com/tech) > [Science](https://www.trendhunter.com/science) ## Key Themes ### What's Driving This Trend - **Flexible Batch Processing:** Modular coating systems that operate across wide volume ranges create new value in pharmaceutical production by accommodating variable demand, smaller product runs, and portfolio complexity. - **Seamless Scale-up:** Consistent process principles between pilot and commercial equipment reduce formulation risk and open pathways for faster transitions from development to manufacturing. - **Contained Potent Handling:** Advanced closed handling and high-containment options support safer processing of potent compounds while enabling manufacturers to expand into specialized therapeutic categories. ### Who This Affects Most - **Pharmaceutical Manufacturing:** Adaptable tablet coating platforms strengthen production agility as drugmakers manage more diverse pipelines, fluctuating batch sizes, and stricter quality expectations. - **Contract Development Manufacturing:** CDMOs gain competitive differentiation from equipment ecosystems that support pilot testing, rapid changeovers, and reliable scale-up for multiple client programs. - **Processing Equipment:** Pilot-scale machinery with interchangeable components and commercial-aligned parameters signals growth potential for suppliers offering integrated, lifecycle-based manufacturing solutions. ## Related on Trend Hunter - [Paper-Based Barrier Drink Packaging](https://www.trendhunter.com/trends/tetra-pak-and-sterilgarda-alimenti.md) - [Adjustable Emulsification Turbines](https://www.trendhunter.com/trends/turbomek.md) - [12-Nozzle Desktop 3D Printers](https://www.trendhunter.com/trends/palette-300.md) - [Performance-Driven Screen Technologies](https://www.trendhunter.com/trends/inkjet-printing.md) - [Mobile-First Installation Platforms](https://www.trendhunter.com/trends/scorpion-scan.md) - [Speedy Stretch Wrapper Systems](https://www.trendhunter.com/trends/signode-octopus-prestige.md) - [Smart Pilot-Scale Extrusion](https://www.trendhunter.com/trends/Smart-pilot-scale-extrusion.md) - [Coated Microfluidic 3D Prints](https://www.trendhunter.com/trends/print-develop-coat-process.md) - [Workplace Design Showcases](https://www.trendhunter.com/trends/kettal-neocon-eames-office.md)